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Pistons vs Bulls Prediction, Picks & Odds for Tonight’s NBA Game

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The All-Star break did nothing to slow down the relentless Detroit Pistons, who’ll look to extend their lead at the top of the East tonight against the rebuilding Chicago Bulls.

Detroit brings a 19-7 road record to the United Center, and my Pistons vs. Bulls predictions signal one-way traffic for Cade Cunningham & Co. as Chicago aims for better draft lottery positioning.

Get my free NBA picks for Saturday, February 21.

Pistons vs Bulls prediction

Pistons vs Bulls best betPistons -10.5 (-115)

The Detroit Pistons’ intensity has been grinding opponents down all year, and there’s every reason to expect a similar script tonight against a Chicago Bulls team that’s 1-9 ATS in its last 10 games.

In contrast, Detroit has covered the spread in six of its past seven victories. After the visitors’ double-digit wins over the New York Knicks (twice) and Toronto Raptors this month, I’ll happily lay the points here.

Chicago turned its roster upside down at the trade deadline, and the hosts are on a seven-game losing skid. Tonight’s mismatch doesn’t feel like a chance to turn things around.

Pistons vs Bulls same-game parlay

With MVP-eligibility question marks surrounding SGA and Nikola Jokic, Cade Cunningham is still in the mix. I’m riding with a do n’t-forget-about-me SGP here after Cade downed the Knicks on Thursday with a 42-8-13 masterpiece.

Cunningham has scored 28+ points in five of his last six outings, and he’s hauled in 5+ rebounds in five straight games. As the cherry on top, he’s knocked down a combined 11 3-pointers in his past two contests.

Pistons vs Bulls SGP

  • Cade Cunningham Over 25.5 points
  • Cade Cunningham Over 1.5 threes
  • Cade Cunningham Over 4.5 rebounds

Our "from downtown" SGP: Three's a Crowd!

The 3-ball hasn’t been a big part of Detroit’s success this year, but tonight is a rare opportunity to let it fly against a Chicago team that’s allowing the highest opponent 3-point percentage in the league at 38%.

This sharpshooting SGP leans into a Pistons offense that shot 43% from downtown earlier this week at MSG, as well as steady sniping from Tre Jones, who’s had a 3-pointer in four of his last five outings.

Pistons vs Bulls SGP

  • Cade Cunningham Over 1.5 threes
  • Tobias Harris Over 1.5 threes
  • Duncan Robinson Over 2.5 threes
  • Tre Jones Over 0.5 threes

Pistons vs Bulls odds

  • Spread: Pistons -10.5 (-115) | Bulls +10.5 (-105)
  • Moneyline: Pistons -550 | Bulls +415
  • Over/Under: Over 230.5 (-110) | Under 230.5 (-110)

Pistons vs Bulls betting trend to know

The Pistons are 5-1 ATS in their last six meetings with the Bulls. Find more NBA betting trends for Pistons vs. Bulls.

How to watch Pistons vs Bulls

LocationUnited Center, Chicago, IL
DateSaturday, February 21, 2026
Tip-off8:00 p.m. ET
TVFDSN DT, CHSN

Pistons vs Bulls latest injuries

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