Fatmata Janneh added 17 points for the Aggies, who shot 64% from three-point range in the first half.
Despite a late 10-0 run by Tennessee, A&M closed the game on a 6-0 run to secure their first road win over a ranked team since January 2021.
Pryor's 22 points lead Texas A&M past No. 21 Tennessee
Ny'Ceara Pryor scored 22 points and dished 10 assists to lead Texas A&M to an 82-74 win over No. 21 Tennessee on Thursday night.