Donovan Mitchell to miss Cavaliers' matchup versus Pistons with groin injury

Donovan Mitchell will miss the Cleveland Cavaliers' big Friday matchup with the Detroit Pistons. Mitchell is listed as out for the game on the NBA injury report with a groin issue.

Additionally, James Harden is listed as questionable with a fractured right thumb. Also questionable on the report are Keon Ellis (left index finger fracture), Dennis Schröder (ankle sprain) and Dean Wade (ankle sprain). 

The Cavaliers (37-23) currently hold the No. 4 seed in the Eastern Conference, 7.5 games behind the NBA-best Pistons (43-14). 

[Subscribe to Yahoo Sports NBA on YouTube]

Mitchell also missed Wednesday's 118-116 loss to the Milwaukee Bucks, the second end of a back-to-back following Tuesday's 109-94 blowout win over the New York Knicks. He has appeared in 55 of the Cavaliers' games this season, averaging 28.5 points (seventh best in the NBA), 4.5 rebounds and 5.8 assists while shooting 37% on a league-leading 517 3-point attempts. 

Cleveland has been on a hot run going into Friday's matchup, winning 15 of its past 20 games. The Cavs haven't lost consecutive games since Dec. 25-27, when they fell to the Knicks and Rockets. 

Since being acquired by Cleveland at the NBA trade deadline, Harden has appeared in seven games, averaging 18.9 points, 4.6 rebounds and 8 assists. He's shooting 49% on 41 3-point attempts. Overall, Harden has played 51 games this season, 44 of them with the Los Angeles Clippers. The Cavaliers have gone 6-2 since he joined the team.

[Get more Cavaliers news: Cleveland team feed]

Evan Mobley is not listed on the injury report after missing Wednesday's game with left calf injury management. He is Cleveland's third-leading scorer this season, averaging 17.5 points per game with 8.6 rebounds, 3.9 assists and 1.8 blocks. 

The Pistons have a clean injury report as of Thursday. Isaiah Stewart is out while serving the sixth game of his seven-game suspension for leaving the bench during the Feb. 11 game between Detroit and the Charlotte Hornets. 

Detroit has also won 15 of its past 20 games.